Fecal microbiota transplantation in patients with blood disorders inhibits gut colonization with antibiotic-resistant bacteria: results of a prospective, single-center study Authors: Jarosław Biliński, Paweł Grzesiowski, Nikolaj Sorensen, Krzysztof Mądry, Jacek Muszyński, Katarzyna Robak, Marta Wróblewska, Tomasz Dzieciątkowski, Grażyna Dulny, Jadwiga Dwilewicz-Trojaczek, Wiesław Wiktor-Jędrzejczak, Grzegorz W. Basak Clinical Infectious Diseases 2017 Impact of gut colonization by […]
Antibiotic-resistant bacteria (ARB) infections are becoming an increasingly intense problem for health care facilities worldwide. Multi-drug resistant organisms (MDRO) are prevalent, including methicillin-resistant Staphylococcus aureus (MRSA), Clostridioides difficile (C. difficile), Carbapenem-resistant Enterobacteriaceae (CRE), vancomycin-resistant Enterococci (VRE) and Gram-negative bacteria producing extended-spectrum β-lactamases (ESBL). These bacteria are resistant to more than three antibiotics, making treatment less […]
Graft-Versus-Host Disease (GvHD) is one of the most common complications after allogeneic hematopoietic cell transplantation (alloHCT). It is life-threatening for up to 50% of patients. The disease is usually treated with steroids, but steroid resistance or steroid dependence is observed in 40-60% of cases. In recent years, scientists have proven that fecal microbiota transplantation (FMT) […]
Fecal microbiota transplantation (FMT), based on strong scientific evidence, has been recognized as an appropriate treatment for recurrent Clostridioides difficile infections by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the American College of Gastroenterology (ACG, view link). In Poland, in 2020, the relevant guidelines of the Polish Society of Epidemiology and […]
Approximately 11.2% of people worldwide suffer from Irritable Bowel Syndrome (IBS), which is associated with a significant reduction in the quality of patients’ life due to discomfort and abdomen pain, irregular bowel movements (diarrhea or constipation), and flatulence. Irritable Bowel Syndrome is a chronic, non-inflammatory disease. Depending on the form of the disease, symptomatic treatment […]
The research results so far show that inflammatory bowel diseases (IBD) may be a potential future indication for fecal microbiota transplantation (FMT). As the name suggests, they are characterized by recurrent inflammation, including ulcerative colitis (UC) and Crohn’s disease (CD). Reduced bacterial diversity was noted in both diseases, in particular a reduction in the Bacteroidetes […]
SIBO (Small Intestinal Bacterial Overgrowth) is a disease of unknown etiology, and its incidence is difficult to estimate due to the lack of ideal diagnostic methods. The disease is characterized by an increased amount of bacteria in the small intestine, manifesting gastrointestinal symptoms including abdominal discomfort, gas, excessive gas production, diarrhea and indigestion of varying […]
Interactions between the brain and the gut have been confirmed, showing that the exchange of information between these seemingly distant organs is two-way. The functioning of the gut-brain axis is described on the basis of the operation of three parallel paths: the nervous, immune and endocrine pathways. Additionally, the presence of intestinal dysbiosis predisposes to […]
Immunooncology is a new field of science focusing on the activation mechanisms of the immune system, which has natural anti-cancer defense mechanisms. The development of many neoplastic diseases depends on the fact that immune system loses control over cancer. Modern anti-cancer immunotherapies enhance the immune response by targeting it directly at cancer cells. Treatment of […]
